Compendium of Study on CBD in Pain Management


CBD is one of the compounds obtained from either the industrial or homegrown cannabis plant. The substance appears to be the quick and natural remedy from stress to mental disorders. Even though it is recently becoming legal in several countries, most people who use CBD is to treat a medical condition for managing pain.

Because of the different classes of pain don’t always respond to medication the same way. It can be challenging to make a broad conclusion of the effect of CBD on pain.

Classes of Pain

  • Neuropathic Pain: This pain is from injury or swelling of the nerves.
  • Acute Pain: This pain happens as an outcome of an injury or tissue damage. A broken bone or arthritis induced by friction on the bones.
  • Centralized Pain: It is something more like fibromyalgia or some of the other chronic pain conditions. This includes migraines, tension headaches that have been more difficult to identify.

CBD for Chronic Pain Relief

In 2018, there is a survey on how CBD works to ease chronic pain. The survey examined inquiries conducted between 1975 and March 2018. These studies analyzed various types of pain, such as cancer pain, neuropathic pain, and fibromyalgia. Based on those studies, experts concluded that CBD was useful in pain management and did not produce adverse side effects.

CBD for Arthritis Pain Relief

Research and development surveyed at CBD use in rats with arthritis. Experts gave CBD to rats for four days, and there were no apparent side effects occurred. The analyst noted the reduced swelling and pain in the subjects’ affected joints. In conclusion, the pain-relieving effects of CBD and its anti-inflammatory factor could benefit people with arthritis. Yet, more research and studies are needed for human subjects.

CBD Pain Relief for Cancer Treatment

Some people with cancer also use CBD. The National Cancer Institute (NCI)Trusted Source has led to CBD as a viable option for reducing chemotherapy side effects like pain. In a study on cancer-related pain, study subjects presented oral sprays of a mixture of THC-CBD extract. This study showed that using the extract rendered more effective pain relief than using opioids alone.

CBD for Migraine Pain Relief

The reviews that currently exist also view at CBD when it’s paired with THC, not when it’s used alone. Yet, results from a 2017 study show that CBD and THC can drive to less acute pain and less severe pain for people with migraines.

The Endocannabinoid System (ECS)

ECS is an intricate network of neurological pathways for the balance of body systems. This system is so prominent to be reliable for the essential functions of both the nervous system and the immune system.

Also, the ECS is a link to the feeling of pain no matter the cause is. It acts by transferring proteins and enzymes from nerve to nerve. The ECS promotes directions from the brain to the body. These directives are responsible for primary motor functions and pain sensations.

Studies have explained that CBD supports the pathways of the ECS. But, it also serves as an anti-inflammatory agent as well. Moreover, cannabis assists cells in their regeneration processes. CBD provides healthy cells with added stimulation. Healthy cells need to proceed with the recovery in affected areas of the body.

CBD Interaction with The ECS

Some researchers think that CBD interacts with a centre part of the ECS in the brain and the immune system. Receptors are small proteins attached to the body tissues. They receive chemical signals from various stimuli and improving the cells’ respond. This response generates anti-inflammatory and pain-relieving effects that support pain management. It indicates that CBD may benefit someone with chronic pain.

When it comes to CBD and pain management, these promising results, as well as the conditions of pain, works with the ECS.

Bottom Line

According to a study, chronic pain is the most frequent basis for medicinal cannabis use. Natural therapies may help promote a better quality of life for some people who endure pain.

Researchers have described that cannabis grown by an academy is feeble and is more limited, unlike cannabis seeds. Furthermore, like hemp — a type of cannabis known for its low levels of THC. Another concern is that a large part of studies uses synthetic cannabinoids rather than medical marijuana — an organic plant that can contain more than 400 distinct chemical compounds.